What is NAD+ Injection?
NAD+ injection is a medical or wellness therapy that delivers nicotinamide adenine dinucleotide (NAD+) directly into the body via intramuscular (IM) or intravenous (IV) routes.
NAD+ is a vital coenzyme found in all living cells, essential for various biological functions such as energy production, DNA repair, and maintaining overall metabolic health.
These injections are widely used in functional medicine and wellness practices for their potential to support cellular regeneration, reduce fatigue, and promote cognitive clarity.
What’s The Difference Between NAD+ Injection and NAD+ IV Drip Therapy?
The main difference between NAD+ injection and NAD+ IV drip therapy lies in the method of delivery, duration, and absorption speed.
- NAD+ Injection is typically administered intramuscularly (IM) in a single, quick shot. It delivers a concentrated dose that absorbs rapidly and is ideal for those seeking convenience and time efficiency.
- NAD+ IV Drip Therapy involves intravenous infusion over a longer period (typically 1–4 hours). This method allows for gradual absorption, making it suitable for higher dosages or patients sensitive to faster NAD+ uptake.
While both methods aim to increase cellular NAD+ levels, IV drip therapy offers more controlled delivery, whereas injections are faster and more cost-effective but may cause mild discomfort or a “flush” due to the sudden boost.
How Does NAD+ Injection Work?
NAD+ injections bypass the digestive tract, allowing NAD+ to enter systemic circulation efficiently. NAD+ plays a critical role in mitochondrial energy production by supporting oxidative phosphorylation and ATP synthesis.
It also supports the activity of sirtuins and PARP enzymes involved in cellular stress response, DNA repair pathways, and inflammation regulation. Through these mechanisms, NAD+ helps maintain metabolic balance, redox homeostasis, and cellular resilience.
How Long Does It Take For NAD Injections To Work?
NAD+ injections can begin working within 15 to 30 minutes after administration, depending on the individual’s metabolism, dosage, and health status.
Many users report feeling increased energy, mental clarity, and reduced brain fog within a few hours of the first injection. However, optimal effects such as improved sleep, mood, or recovery often require multiple sessions over days or weeks, especially for chronic fatigue, addiction support, or anti-aging protocols.
Response time can also vary based on whether NAD+ is administered intramuscularly (IM) or intravenously (IV), with IM injections generally acting faster, but IV drips offering a more gradual, sustained release.
What are The Benefits Of NAD+ Injection?
- NAD+ injections stimulate ATP production by improving mitochondrial respiration
- They enhance cognitive sharpness, focus, and memory retention
- NAD+ reduces systemic fatigue and accelerates physical and mental recovery
- It repairs DNA damage and activates cellular regeneration, supporting longevity
- NAD+ modulates neurotransmitter levels like serotonin and dopamine, stabilizing mood
- It supports hepatic detoxification by boosting phase I and II liver enzymes
- NAD+ regulates fat metabolism and optimizes insulin sensitivity, aiding weight control
- It reduces cravings and eases withdrawal during addiction recovery protocols
- NAD+ activates immune defense pathways and neutralizes oxidative damage
- It controls sirtuin and PARP pathways, directly linked to aging and inflammation
Studies suggest that NAD+ levels decline by over 50% by middle age, reducing mitochondrial function (Verdin et al., 2018). By replenishing NAD+ stores, Dr. Syra Aesthetics supports the body’s natural energy production, brain function, and longevity mechanisms.
What are NAD Injections Good For?
NAD+ injections increase mitochondrial efficiency, support DNA repair, and modulate inflammatory responses. They are used for weight loss, fertility, skin rejuvenation, and chronic fatigue by acting on cellular metabolism.
For weight loss, NAD+ enhances lipolysis, improves metabolic flexibility, and stabilizes glucose levels. Clinics combine it with calorie restriction and exercise for better fat loss outcomes.
In fertility, NAD+ improves egg quality, boosts sperm motility, regulates hormone function, and reduces age-related cellular decline in reproductive tissues.
For skin health, NAD+ stimulates collagen production, enhances dermal hydration, and repairs UV-induced DNA mutations, making it a core treatment in anti-aging protocols.
In chronic fatigue syndrome, NAD+ restores ATP output, balances the autonomic nervous system, and lowers oxidative stress, leading to sustained energy and mental clarity.
Are NAD+ injections worth it?
Yes, NAD+ injections can be worth it for specific goals like energy restoration, mental clarity, and addiction recovery, especially when rapid effects are desired. However, benefits depend on dosage, individual NAD+ levels, and medical supervision.
NAD⁺ Injection Ingredients
- Nicotinamide Adenine Dinucleotide (NAD⁺)
- Sterile Water for Injection or 0.9% Sodium Chloride (Saline)
NAD+ injections are not recommended for individuals who are pregnant or breastfeeding, undergoing cancer treatment, have severe liver or kidney disease, or suffer from uncontrolled diabetes, hypertension, or cardiovascular issues.
People with known allergies to NAD+ compounds or those under 18 years old should avoid this treatment unless medically supervised. Medical consultation is essential to ensure NAD+ injections are appropriate and safe based on your individual health profile.
The frequency of NAD+ injections depends on your health goals, baseline NAD+ levels, and how your body responds to treatment. For general wellness and energy support, most individuals start with 2–3 injections per week during the first month, followed by a maintenance phase of 1 injection per week or biweekly.
NAD+ Injection Frequency & Dosage Chart
Use Case
Initial Phase (Weeks 1–4)
Maintenance Phase
Typical Dosage
General Wellness & Energy
2–3x per week
1x per week or biweekly
100–250 mg per injection
Anti-Aging / Cognitive Support
2–3x per week
1-2x per week
250-500 mg
Chronic Fatigue / Burnout
3–5x per week
1-2x per week
250-750 mg
Addiction Recovery (Intensive)
Daily for 7–14 days
2–3x per week thereafter
500–1000+ mg
At Dr. Syra Aesthetics, dosing frequency is determined based on your medical history, lifestyle factors, and lab diagnostics when applicable. We don’t use one-size-fits-all protocols; each session is adjusted to optimize safety and results.
Common side effects include:
- Nausea
- Head pressure
- Muscle soreness
- Flushing or sweating
- Chest tightness (especially with fast IV drip)
Slower administration reduces most reactions.
After NAD+ injections, most users experience elevated energy, mental clarity, and improved mood within hours. Some may report temporary fatigue or mild headache due to detox effects. Proper hydration improves outcomes and extends benefits over several days.
Yes, when performed in a medically regulated clinic like Syra Aesthetics. All NAD+ injections are carried out by trained staff using sterile, pharmaceutical-grade formulations. We monitor patients during and after treatment to ensure comfort and manage any reactions.
Effects last from 3 to 14 days, depending on dosage, baseline NAD+ levels, and metabolic rate. Higher doses and multiple sessions extend the duration of benefits.
Real Results, Real Feedback
Trishana B.
I loved my first experience at Syra Aesthetic! I had Dr. Hanif as my provider, and she thoroughly educated me on a treatment plan for my concerns. We did a Morpheus8 radiofrequency microneedling treatment, and I loved the results. I have already booked another treatment in a month from now!
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I would like to thank to the Dr Syra Hanif's first doing a great treatment of one of my sister at her office we do not reviews but my sis insist me to write about her services as my sis loved it thank you for making her happy we wish you may go higher and higher. your staff is cooperative Harry called us and he was sweet asking about the services and feedback stuff it was great and we will again for further procedures :)
See ReviewMars
Syra Aesthetics is a name of professionalism. It is phenomenal in treating actual usage of the experience. I recommend people who need care with soft hands should visit here. Harry, you are great at explaining things more clearly overall. You nailed it.
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